Jacob Kirkland Ph.D. (He/Him/His)
Jake was an undergrad at UC Berkeley (Go Bears!), then spent over three years as a technician in the Corvera Lab at UCSF in the Department of Surgery studying electrophysiology and GPCR biology in hepatobiliary and digestive diseases. He then went on to get his PhD in the Kamakaka Lab at UCSC studying insulators and chromatin organization in budding yeast. There he found the unexpected observation that heterochromatin organization requires both DNA elements and Homologous Recombination DNA repair proteins. Jake then moved to one more SF Bay Area University to do his postdoctoral work in the Crabtree Lab at Stanford University. In the Crabtree lab, Jake developed a Cas9 based epigenome editing technology that allows for the rapid and reversible recruitment of proteins to any locus of interest. Jake also worked closely with the Curtis lab at Stanford to describe a breast cancer specific chromatin regulator transcriptional network that predicts patient response to anthracyclines through a novel mechanism involving changes in DNA accessibility to TOP2 proteins.
Jake believes in hobbies outside of the lab and is an avid birder, herper, camera trapper, and all around naturalist. Here a few examples of his wildlife photography. Jake is a homebrewer of actually drinkable beer, and a hobbiest amphibian and reptile breeder.
Google Scholar Profile
Joined May 2021
Joined June 2021
Laura Pistoni M.Sc.
Senior Research Technician
Joining September 2021