Publications
(20) Moon, E.J., Mello, S.S., Li, C.G., Chi, J-T., Thakker, K., Kirkland, J.G., et al. The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling. Nat Commun 12, 4308 (2021). https://doi.org/10.1038/s41467-021-24631-6 PMID: 34262028
19) Weber CM, Hafner A, Kirkland JG, Braun SMG, Stanton BZ, Boettiger AN, Crabtree GR mSWI/SNF promotes polycomb repression both directly and through genome-wide redistribution, Nat Struct Mol Biol 28, 501–511 (2021) https://doi.org/10.1038/s41594-021-00604-7 PMID: 34117481
(18) Chory EJ, Kirkland JG, Chang CY, et al. Chemical Inhibitors of a Selective SWI/SNF Function Synergize with ATR Inhibition in Cancer Cell Killing, ACS Chem Bio 2020 Jun 19;15(6):1685-1696. doi:10.1021/acschembio.0c00312. Epub 2020 May 27. PMID: 32369697
(17) Seoane J* & Kirkland JG*, Caswell-Jin, JL, Crabtree GR, Curtis CN, Chromatin Regulators Mediate Anthracycline Sensitivity in Breast Cancer; Nature Medicine Nat Med 25, 1721–1727 (2019) (*Co-first authors) PMID: 31700186
(16) Hamdani O*, Dhillon N*, Hsieh T-H*, Fujita T*, Ocampo J*, Kirkland JG, Lawrimore J, Kobayashi T, Friedman B, Fulton D, Wu K, Chereji R, Oki M, Bloom K, Clark D, Rando O, Kamakaka RT. Transfer RNA Genes Affect Chromosome Structure and Function via Local Effects; Molecular Cell Biology. February 2019, (*Co-first authors) PMID: 30718362
(15) Hodges C* & Stanton B*, Cermakova K, Chang C, Miller E, Kirkland JG, Lim Ku WL, Veverka V, Zhao K, Crabtree GR, Dominant-negative Smarca4 (Brg1) mutations induce convergent effects on the enhancer accessibility landscape, Nature Structural and Molecular Biology, January 2018, (*Co-first authors) PMID: 29323272
(14) Braun SMG* & Kirkland JG*, Chory EJ, Husmann D, Calarco JP & Crabtree GR, Rapid and reversible epigenome editing by endogenous chromatin regulators, Nature Communications September 2017, (*Co-first authors) PMID: 28916764
(13) Hodges C, Kirkland JG and Crabtree GR, The many roles of BAF (mSWI/SNF) and PBAF complexes in cancer, Cold Spring Harb Perspect Med August 2016 PMID: 27413115
(12) Kirkland JG*, Peterson* MR, Still II* CD, Brueggeman* L, Dhillon N, and Kamakaka RT Heterochromatin formation via recruitment of DNA repair proteins, Molecular Biology of the Cell 26(7) · January 2015, (*Co-first authors) PMID: 25631822
(11) Snider CE, Stephens A, Kirkland JG, Hamdani O, Kamakaka RT, Bloom K, Dyskerin, tRNA genes and condensin tether pericentric chromatin to the spindle axis in mitosis, Journal of Cell Biology, 2014 Oct 14 PMID: 25332162
(10) Kirkland JG and Kamakaka RT, Long-range heterochromatin association is mediated via silencing and double strand DNA break repair proteins, J Cell Biol 2013 Jun 10; 201(6) 809-26 PMID: 23733345
(9) Kirkland JG, Raab J, Kamakaka RT, TFIIIC bound DNA elements in nuclear organization and insulation Biochim Biophys Acta. 2012 Sep 21. doi:pii: S1874-9399(12)00166-6 PMID: 23000638
(8) Cottrell GS*, Alemi F*, Kirkland JG*, Grady EF, Corvera CU, and Bhargava A, Localization of Calcitonin Receptor-like Receptor (CLR) and Receptor Modifying Protein (RAMP1) in Human Gastrointestinal Tract, Peptides, Peptides (2012), (*Co-first authors) PMID: 22484227
(7) Ruben GJ, Kirkland JG, MacDonough T, Chen M, Dubey RN, Gartenberg MR and Kamakaka RT, Nucleoporin mediated nuclear positioning and silencing of HMR, PLoS One. 2011;6(7):e21923. Epub 2011 Jul 19. PMID: 21818277
(6) Poole DP, Godfrey C, Cattaruzza F, Cottrell GS, Kirkland JG, Pelayo JC, Bunnett NW and Corvera CU. Expression and Function of the Bile Acid Receptor GpBAR1 (TGR5) in the Murine Enteric Nervous System. Neurogastroenterology and Motility PMID: 20236244
(5) Kirkland JG and Kamakaka RT, tRNA insulator function: insight into inheritance of transcription states? Epigenetics 2010 Feb 27;5(2) PMID: 20168086
(4) Kirkland JG, Godfrey CB, Garrett R, Karkar S, Yeh BM, Corvera CU, Reversible Model of Biliary Inflammation and Obstructive Jaundice in Mice J Surg Res, 2009 Sept, 11 PMID: 19932898
(3) Chang T, Sawhney R, Monto A, Davoren J, Kirkland JG, Stewart L, Corvera CU, “Implementation of a Multidisciplinary Treatment Team for Hepatocellular Cancer at a Veterans Affairs Medical Center Improves Survival” HPB PMID: 19088925
(2) Kirkland JG, Cottrell G, Bunnett N, Corvera C, Agonists of protease-activated receptors 1 and 2 stimulate electrolyte secretion from mouse gallbladder, Am J Physiol Gastrointest Liver Physiol. 2007 Apr 12; PMID: 17431214
(1) Corvera CU, Dada S, Kirkland JG, Garrett R, Way L, Stewart L, Bipolar Pulse Coagulation for Resection of the Cirrhotic Liver, Journal of Surgical Research, December 2006; 136(2):182-6; PMID: 17054993
